Gene regulation

Timing

During early development, cells begin to take on specific functions. Gene regulation ensures that the appropriate genes are expressed at the proper times. Gene regulation can also help an organism respond to its environment. Gene regulation is accomplished by a variety of mechanisms including chemically modifying genes and using regulatory proteins to turn genes on or off.


The epicenter of epigenetics

Interview with Randy Jirtle

I am thrilled and honored to podcast with Dr. Randy Jirtle. The field of epigenetics has exploded in the last decade, initiated almost exclusively by the groundbreaking research of Randy and his colleague Robert Waterland. Their 2003 study on the effects of nutrition on epigenetic gene regulation in agouti mice is the most cited paper in the history of science, and his trailblazing discoveries have expanded our understanding of human health and the etiology of disease. Listen to my fascinating conversation with Dr. Randy Jirtle.