Gene Editing with CRISPR

The revolutionary gene-editing tool known as CRISPR can alter, add, and remove genes from the human genome. The implications are immense: It could help eliminate illnesses like sickle cell disease and muscular dystrophy, and could even allow us to alter the genes of future generations of humans, leading to so-called designer babies. But will this ever really happen?

Gene editing +

The CRISPR-Cas9 system has revolutionised gene-editing, but cutting DNA isn’t all it can do. From turning gene expression on and off to fluorescently tagging particular sequences, this animation explores some of the exciting possibilities of CRISPR.

Immortality: Martine Rothblatt

The founder of Sirius XM satellite radio, Martine Rothblatt now heads up a drug company that makes life-saving medicines for rare diseases (including one drug that saved her own daughter’s life). Meanwhile she is working to preserve the consciousness of the woman she loves in a digital file … and a companion robot. In an onstage conversation with TED’s Chris Anderson, Rothblatt shares her powerful story of love, identity, creativity, and limitless possibility.

ARCUS therapeutic-grade genome editing

ARCUS is a unique, highly specific and versatile genome editing platform created by Precision BioSciences. The platform delivers therapeutic-grade genome editing.

In contrast to editing platforms that focus on ease of design and quick turnaround, the ARCUS approach is centered on safety, delivery, and control of edits – the things that we believe matter most to patients and their physicians.

ARCUS nucleases have the potential to deliver safer, more specific genetic edits by leveraging the properties of a naturally occurring gene editing enzyme – the homing endonuclease I-CreI – which evolved in nature to make a single, highly specific DNA edit before using its built-in safety switch to shut itself off.