Targeting misfolded proteins

Proclara takes a novel approach to treating protein misfolding diseases, based on the fact that many toxic aggregates of misfolded proteins share a common characteristic – the amyloid protein fold – that represents a unique target for drug development.

Proclara scientists have developed a novel proprietary technology known as GAIM, or General Amyloid Interaction Motif, that simultaneously targets multiple misfolded proteins implicated in both neurodegenerative and progressive peripheral diseases, potentially creating a more robust response that could be suitable for patients at all stages of disease.

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