ARCUS therapeutic-grade genome editing

ARCUS is a unique, highly specific and versatile genome editing platform created by Precision BioSciences. The platform delivers therapeutic-grade genome editing.

In contrast to editing platforms that focus on ease of design and quick turnaround, the ARCUS approach is centered on safety, delivery, and control of edits – the things that we believe matter most to patients and their physicians.

ARCUS nucleases have the potential to deliver safer, more specific genetic edits by leveraging the properties of a naturally occurring gene editing enzyme – the homing endonuclease I-CreI – which evolved in nature to make a single, highly specific DNA edit before using its built-in safety switch to shut itself off.